Familial Hypercholesterolaemia Genetic Testing Programme

Vaccination and Childhood Developmental Screening Subsidies (VCDSS)

Singapore National Asthma Programme (SNAP)

Antimicrobial Utilisation Surveillance Initiative

Last updated on 03 July 2025

In line with the Ministry of Health’s efforts to enhance preventive care, a new National Familial Hypercholesterolaemia (FH) Genetic Testing Programme has been introduced to support early identification of patients with FH, with effect from 30 June 2025.

FH is an inherited genetic condition causing impaired LDL-cholesterol (LDL-C) metabolism and predisposes to early onset atherosclerotic cardiovascular disease (ASCVD). Early detection of FH through LDL-C screening, gene testing, and cascade screening is crucial for managing FH and reducing the lifetime risk of ASCVD and death.

Resources

The following resources may be useful to you:

MOH Circular No. 33/2025 Introduction of Familial Hypercholesterolaemia (FH) Genetic Testing Service	Click here to download
MOH Circular No. 36/2025 Key Amendments to The Moratorium on Genetic Testing and Insurance	Click here to download
Familial Hypercholesterolaemia Genetic Testing Service: A Guide for Primary Care Providers	Click here to download
Familial Hypercholesterolaemia Brochures	English version Chinese version Malay version Tamil version
Genomic Assessment Centre (GAC) Leaflet	English version Chinese version Malay version Tamil version
Genetic Testing, Insurance and the Moratorium: What You Should Know Pamphlet	English version

Participate in this Scheme

Since 30 June 2025, doctors can refer Singapore Citizens (SC) or Permanent Residents (PR) to the Genomic Assessment Centre (GAC) @ SingHealth*, if they meet the criteria of LDL-C ≥ 5.5 mmol/L (≥ 212mg/dL).

*This GAC will serve all Singapore Residents (Singapore Citizens and Permanent Residents) until the GACs operated by NUHS and NHG open subsequently.

For further clarification on MOH Circulars relating to Familial Hypercholesterolaemia Genetic Testing Service, please email moh_info@moh.gov.sg.

For further clarification on the Moratorium on Genetic Testing and Insurance, please email HCSA_Enquiries@moh.gov.sg.